Publications of J Weir

Ros, U.; Martinez-Osorio, V.; Valiente, P.; Abdelwahab, Y.; Shalaby, R.; Zanna, S.; Saggau, J.; Wachsmuth, L.; Nemade, H.; Zoeller, J. et al.; Lottermoser, H.; Chen, Y.-G.; Ibrahim, M.; Kelepouras, K.; Vasilikos, L.; Bedoya, P.; Espiritu, R.; Müller, S.; Altmannova, V.; Tielemann, D.; Weir, J.; Langer, J.; Adam, M.; Walczak, H.; Wong, W.-L.; Liccardi, G.; Mollenhauer, M.; Pasparakis, M.; Peltzer, N.; García-Sáez, A.: MLKL activity requires a splicing-regulated, druggable intramolecular interaction. Molecular Cell 85 (8), pp. 1589 - 1605 (2025)

Dereli, I.; Telychko, V.; Papanikos, F.; Raveendran, K.; Xu, J.; Boekhout, M.; Stanzione, M.; Neuditschko, B.; Imjeti, N.; Selezneva, E. et al.; Tuncay, H.; Demir, S.; Giannattasio, T.; Gentzel, M.; Bondarieva, A.; Stevense, M.; Barchi, M.; Schnittger, A.; Weir, J.; Herzog, F.; Keeney, S.; Tóth, A.: Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes. Nature Communications 15 (1), 2941 (2024)

Chen, L.; Weir, J.: The molecular machinery of meiotic recombination. Biochemical Society Transactions 52 (1), pp. 379 - 393 (2024)

Weir, J.: Molekulare Mechanismen der meiotischen Rekombination. Biospektrum 29 (7), p. 816 (2023)

Podobnik, M.; Singh, A.; Fu, Z.; Dooley, C.; Frohnhöfer, H.; Firlej, M.; Stednitz, S.; Elhabashy, H.; Weyand, S.; Weir, J. et al.; Lu, J.; Nüsslein-Volhard, C.; Irion, U.: kcnj13 regulates pigment cell shapes in zebrafish and has diverged by cis-regulatory evolution between Danio species. Development 150 (16), dev.201627 (2023)

Altmannova, V.; Firlej, M.; Mueller, F.; Janning, P.; Rauleder, R.; Rousova, D.; Schaeffler, A.; Bange, T.; Weir, J.: Biochemical characterisation of Mer3 helicase interactions and the protection of meiotic recombination intermediates. Nucleic Acids Research (London) 51 (9), gkad175, pp. 4363 - 4384 (2023)

Clasen, S.; Bell, M.; Borbón, A.; Lee, D.-H.; Henseler, Z.; de la Cuesta-Zuluaga, J.; Parys, K.; Zou, J.; Wang, Y.; Altmannova, V. et al.; Youngblut, N.; Weir, J.; Gewirtz, A.; Belkhadir, Y.; Ley, R.: Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5. Science Immunology 8 (79), eabq7001 (2023)

Kabakci, Z.; Reichle, H.; Lemke, B.; Rousova, D.; Gupta, S.; Weber, J.; Schleiffer, A.; Weir, J.; Lehner, C.: Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin. PLoS Genetics 18 (12), e1010547 (2022)

Rousová, D.; Nivsarkar, V.; Altmannova, V.; Raina, V.; Funk, S.; Liedtke, D.; Janning, P.; Müller, F.; Reichle, H.; Vader, G. et al.; Weir, J.: Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation. eLife 10, e72330 (2021)

Altmannova, V.; Blaha, A.; Astrinidis, S.; Reichle, H.; Weir, J.: InteBac: An integrated bacterial and baculovirus expression vector suite. Protein Science 30 (1), pp. 108 - 114 (2021)

Villar-Fernández, M.; Cardoso da Silva, R.; Firley, M.; Pan, D.; Weir, E.; Sarembe, A.; Raina, V.; Bange, T.; Weir, J.; Vader, G.: Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly. Life science alliance 3 (11), e201900630 (2020)

Pesenti, M.; Prumbaum, D.; Auckla , P.; Smith, C.; Faesen, A.; Petrovic, A.; Erent, M.; Maffini, S.; Pentakota, S.; Weir, J. et al.; Lin, Y.-C.; Raunser, R.; McAinsh, A.; Musacchio, A.: Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80. Molecular Cell 71 (6), pp. 923 - 939 (2018)

Pentakota, S.; Zhou, K.; Smith, C.; Maffini, S.; Petrovic, A.; Morgan, G.; Weir, J.; Vetter, I.; Musacchio, A.; Luger, K.: Decoding the centromeric nucleosome through CENP-N. eLife 6, e33442 (2017)

Weir, J.; Faesen, A.; Klare, K.; Petrovic, A.; Basilico, F.; Fischbock, J.; Pentakota, S.; Keller, J.; Pesenti, M.; Pan, D. et al.; Vogt, D.; Wohlgemuth, S.; Herzog, F.; Musacchio, A.: Insights from biochemical reconstitution into the architecture of human kinetochores. Nature 537 (7619), pp. 249 - 253 (2016)

Pesenti, M.; Weir, J.; Musacchio, A.: Progress in the structural and functional characterization of kinetochores. Current Opinion in Structural Biology 37, pp. 152 - 163 (2016)

Breit, C.; Bange, T.; Petrovic, A.; Weir, J.; Müller, F.; Vogt, D.; Musacchio, A.: Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1. PLoS One 10 (12), e0144673 (2015)

Klare, K.; Weir, J.; Basilica, F.; Zimniak, T.; Massimiliano, L.; Ludwigs, N.; Herzog, F.; Musacchio, A.: CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores. The Journal of Cell Biology: JCB 210 (1), pp. 11 - 22 (2015)

Falk, S.; Weir, J.; Hentschel, J.; Reichelt, P.; Bonneau, F.; Conti, E.: The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities. Molecular Cell 55 (6), pp. 856 - 867 (2014)

Basilico, F.; Maffini, S.; Weir, J.; Prumbaum, D.; Rojas, A.; Zimniak, T.; De Antoni, A.; Jeganathan, S.; Voss, B.; Van Gerwen, S. et al.; Krenn, V.; Massimiliano, L.; Valencia, A.; Vetter, I.; Herzog, F.; Raunser, S.; Pasqualato, S.; Musacchio, A.: The pseudo GTPase CENP-M drives human kinetochore assembly. eLife 3, e02978 (2014)

Primorac, I.; Weir, J.; Chiroli, E.; Gross, F.; Hoffmann, I.; Van Gerwen, S.; Ciliberto, A.; Musacchio, A.: Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling. eLife 2, e01030 (2013)