Publications
_{Structural Biochemistry of Meiosis}

Kane, E.; Trefs, L.; Eckert, L.; Coelho, S.; Weir, J.: Characterization of meiotic axis proteins in the model brown alga Ectocarpus. EMBO Reports 26 (23), pp. 5673 - 5702 (2025)

Selezneva, E.; Feygina, E.; Ageeva, L.; Rozov, F.; Kopylova, I.; Semenov, A.: Neprilysin 2 catalyses the degradation of natriuretic peptides despite sacubitrilat Inhibition. Scientific Reports 15, 27401 (2025)

Ros, U.; Martinez-Osorio, V.; Valiente, P.; Abdelwahab, Y.; Shalaby, R.; Zanna, S.; Saggau, J.; Wachsmuth, L.; Nemade, H.; Zoeller, J. et al.; Lottermoser, H.; Chen, Y.-G.; Ibrahim, M.; Kelepouras, K.; Vasilikos, L.; Bedoya, P.; Espiritu, R.; Müller, S.; Altmannova, V.; Tielemann, D.; Weir, J.; Langer, J.; Adam, M.; Walczak, H.; Wong, W.-L.; Liccardi, G.; Mollenhauer, M.; Pasparakis, M.; Peltzer, N.; García-Sáez, A.: MLKL activity requires a splicing-regulated, druggable intramolecular interaction. Molecular Cell 85 (8), pp. 1589 - 1605 (2025)

Dereli, I.; Telychko, V.; Papanikos, F.; Raveendran, K.; Xu, J.; Boekhout, M.; Stanzione, M.; Neuditschko, B.; Imjeti, N.; Selezneva, E. et al.; Tuncay, H.; Demir, S.; Giannattasio, T.; Gentzel, M.; Bondarieva, A.; Stevense, M.; Barchi, M.; Schnittger, A.; Weir, J.; Herzog, F.; Keeney, S.; Tóth, A.: Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes. Nature Communications 15 (1), 2941 (2024)

Chen, L.; Weir, J.: The molecular machinery of meiotic recombination. Biochemical Society Transactions 52 (1), pp. 379 - 393 (2024)

Weir, J.: Molekulare Mechanismen der meiotischen Rekombination. Biospektrum 29 (7), p. 816 (2023)

Podobnik, M.; Singh, A.; Fu, Z.; Dooley, C.; Frohnhöfer, H.; Firlej, M.; Stednitz, S.; Elhabashy, H.; Weyand, S.; Weir, J. et al.; Lu, J.; Nüsslein-Volhard, C.; Irion, U.: kcnj13 regulates pigment cell shapes in zebrafish and has diverged by cis-regulatory evolution between Danio species. Development 150 (16), dev.201627 (2023)

Altmannova, V.; Firlej, M.; Mueller, F.; Janning, P.; Rauleder, R.; Rousova, D.; Schaeffler, A.; Bange, T.; Weir, J.: Biochemical characterisation of Mer3 helicase interactions and the protection of meiotic recombination intermediates. Nucleic Acids Research (London) 51 (9), gkad175, pp. 4363 - 4384 (2023)

Clasen, S.; Bell, M.; Borbón, A.; Lee, D.-H.; Henseler, Z.; de la Cuesta-Zuluaga, J.; Parys, K.; Zou, J.; Wang, Y.; Altmannova, V. et al.; Youngblut, N.; Weir, J.; Gewirtz, A.; Belkhadir, Y.; Ley, R.: Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5. Science Immunology 8 (79), eabq7001 (2023)

Kabakci, Z.; Reichle, H.; Lemke, B.; Rousova, D.; Gupta, S.; Weber, J.; Schleiffer, A.; Weir, J.; Lehner, C.: Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin. PLoS Genetics 18 (12), e1010547 (2022)

Rousová, D.; Nivsarkar, V.; Altmannova, V.; Raina, V.; Funk, S.; Liedtke, D.; Janning, P.; Müller, F.; Reichle, H.; Vader, G. et al.; Weir, J.: Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation. eLife 10, e72330 (2021)

Altmannova, V.; Blaha, A.; Astrinidis, S.; Reichle, H.; Weir, J.: InteBac: An integrated bacterial and baculovirus expression vector suite. Protein Science 30 (1), pp. 108 - 114 (2021)

Villar-Fernández, M.; Cardoso da Silva, R.; Firley, M.; Pan, D.; Weir, E.; Sarembe, A.; Raina, V.; Bange, T.; Weir, J.; Vader, G.: Biochemical and functional characterization of a meiosis-specific Pch2/ORC AAA+ assembly. Life science alliance 3 (11), e201900630 (2020)

Firlej, M.; Weir, J.: Unwinding during stressful times: Mechanisms of helicases in meiotic recombination. In: Current Topics in Developmental Biology, Vol. 151. Academic Press, New York (2023)

Weir, J.: Insights into Meiosis: Elucidating DNA Repair Modulation via Mass Spectrometry. In GBM Compact: Focus on Proteomics. GBM Compact: Focus on Proteomics, Frankfurt a.M., Germany, September 05, 2023 - September 06, 2023. (2023)

Clasen, S.; Bell, M.; Borbón, A.; Lee, D.-H.; Henseler, Z.; de la Cuesta-Zuluaga, J.; Parys, K.; Zou, J.; Wang, Y.; Altmannova, V. et al.; Youngblut, N.; Weir, J.; Gewirtz, A.; Belkhadir, Y.; Ley, R.: Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5. In Cell Symposia: Infection Biology in the Age of the Microbiome, ST.01. Cell Symposia: Infection Biology in the Age of the Microbiome, Paris, France, June 07, 2023 - June 09, 2023. (2023)

Chen, L.: Choosing the right partner: Biochemical insight into interhomolog bias. BioConnect Seminar: Max Planck Institute for Biology, Tübingen, Germany (2025)

Selezneva, E.: Can Shape Memory Effects Contribute to Improved Self-Healing Properties in Polymer Materials? Matter to Life Lecture Series: Max Planck School Matter to Life, Heidelberg, Germany (2023)

Weir, J.: Mer3 Helicase Antagonises Sgs1 by Binding to Top3-Rmi1. Meiosis Gordon Research Conference: Diverse and Conserved Molecular Mechanisms Preventing Aneuploidy During Gamete Production , New London, NH, USA (2022)

Firlej, M.: Studying the proteins involved in the regulation of meiotic recombination. Research in Action Seminar, Tübingen, Germany (2021)