Selected publications

2019

  • Čapek D, Müller P (2019). Positional information and tissue scaling during development and regeneration. Development, in press.
  • Rogers KW, Müller P (2019). Optogenetic approaches to investigate spatiotemporal signaling during development. Current Topics in Developmental Biology, in press.
  • Landge AN, Jordan BM, Müller P (2019). Pattern formation mechanisms of self-organizing reaction-diffusion systems. Developmental Biology, in press.
  • Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefańczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J (2019). LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. Blood, 134:1159-1175.
  • Müller P, El-Sherif E (2019). A systems-level view of pattern formation mechanisms in development. Developmental Biology, doi: 10.1016/j.ydbio.2019.10.034.
  • Mörsdorf D, Müller P (2019). Tuning protein diffusivity with membrane tethers. Biochemistry, 58:177-181.
  • Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C (2019). A conserved regulatory program initiates lateral plate mesoderm emergence across chordates. Nature Communications, 10:3857.
  • Rogers KW, Müller P (2019). Nodal and BMP dispersal during early zebrafish development. Developmental Biology, 447:17-23.

2018

  • Almuedo-Castillo M, Bläßle A, Mörsdorf D, Marcon L, Soh GH, Rogers KW, Schier AF, Müller P (2018). Scale-invariant patterning by size-dependent inhibition of Nodal signalling. Nature Cell Biology, 20:1032-1042.  
  • Soh GH, Müller P (2018). FRAP analysis of extracellular diffusion in zebrafish embryos. Methods Mol Biol, 1863:107-124. 
  • Piragyte I, Clapes T, Polyzou A, Geltink RIK, Lefkopoulos S, Yin N, Cauchy P, Curtis JD, Klaeylé L, Langa X, Beckmann CCA, Wlodarski MW, Müller P, Van Essen D, Rambold A, Kapp FG, Mione M, Buescher JM, Pearce EL, Polyzos A, Trompouki E (2018). A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nature Communications, 9:3090. 
  • Diego X, Marcon L, Müller P, Sharpe J (2018). Key features of Turing systems are determined purely by network topology. Phys. Rev. X, 8:021071. 
  • Bläßle A, Soh G, Braun T, Mörsdorf D, Preiß H, Jordan BM, Müller P (2018). Quantitative diffusion measurements using the open-source software PyFRAP. Nature Communications, 9:1582. 
  • Ramachandran A, Vizan P, Debipriya D, Chakravarty P, Vogt J, Rogers KW, Müller P, Hinck AP, Sapkota GP, Hill CS (2018). TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition. eLife, 7:e31756. 

2017

  • Pomreinke AP, Soh GH, Rogers KW, Bergmann JK, Bläßle AJ, Müller P (2017). Dynamics of BMP signaling and distribution during zebrafish dorsal-ventral patterning. eLife, 6:e25861. 
  • Donovan P, Dubey OA, Kallioinen S, Rogers KW, Muehlethaler K, Müller P, Rimoldi D, Constam DB (2017). Paracrine Activin-A signaling promotes melanoma growth and metastasis through immune evasion. J Invest Dermatol, 137:2578-2587. 

2016

  • Marcon L, Diego X, Sharpe J, Müller P (2016). High-throughput mathematical analysis identifies Turing networks for patterning with equally diffusing signals. eLife, 5:e14022. 
  • Sako K, Pradhan SJ, Barone V, Inglés-Prieto Á, Müller P, Ruprecht V, Capek D, Galande S, Janovjak H, Heisenberg CP (2016). Optogenetic control of Nodal signaling reveals a temporal pattern of Nodal signaling regulating cell fate specification during gastrulation. Cell Reports,16:866-877.
  • Müller P, Nüsslein-Volhard C (2016). Obituary: Hans Meinhardt (1938-2016). Development, 143:1231-1233. 

2015

  • Bläßle A, Müller P (2015). PyFDAP: Automated analysis of Fluorescence Decay After Photoconversion (FDAP) experiments. Bioinformatics, 15:972-974. 
  • Rogers KW, Bläßle A, Schier AF, Müller P (2015). Measuring protein stability in living zebrafish embryos using Fluorescence Decay After Photoconversion (FDAP). J Vis Exp, 95:52266. 

Before 2015

  • Müller P, Rogers KW, Shuizi RY, Brand M, Schier AF (2013). Morphogen transport. Development, 140:1621-1638.
  • Müller P, Rogers KW, Jordan BM, Lee JS, Robson D, Ramanathan S, Schier AF (2012). Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science, 336:721-724.
  • Xu C, Fan ZP, Müller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI (2012). Nanog regulates endoderm formation through the Mxtx2-Nodal pathway. Dev Cell, 22:625-638.
  • Müller P, Pugazhendhi D, Zeidler MP (2012). Modulation of human JAK/STAT pathway signalling by functionally conserved regulators. JAK-STAT, 1:34-43.
  • Müller P, Schier AF (2011). Extracellular movement of signaling molecules. Dev Cell, 21:145-158.
  • Müller P, Boutros M, Zeidler MP (2008). Identification of JAK/STAT pathway regulators - Insights from RNAi screens. Semin Cell Dev Biol, 19:360-369.
  • Ginsberg M, Czeko E, Müller P, Ren Z, ChenX, Darnell JE Jr. (2007). Amino acid residues required for physical and cooperative interaction of STAT3 and AP-1 proteins c-Jun and c-Fos. Mol Cell Biol, 27:6300-6308.
  • Dietz GP, Valbuena C, Dietz B, Meuer K, Müller P, Weishaupt JH, Bähr M (2006). Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson’s disease. Brain Res, 1082:61-66.
  • Müller P, Kuttenkeuler D, Gesellchen V, Zeidler MP, Boutros M (2005). Identification of JAK/STAT signaling components by genome-wide RNA interference. Nature, 436:871-875.