Yingguang Frank Chan

Position: Research Group Leader
Unit: AG Chan
Address: Max-Planck-Ring 9
72076 Tübingen
Phone: +49 7071 601 888
Fax: +49 7071 601 801
E-Mail: frank.chan[at]tuebingen.mpg.de
Picture of Chan, Yingguang Frank

Education and Training


2012-Present • Max Planck Research Group Leader, Friedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany

2009-2012    • Postdoctoral Research Fellow, Max Planck Institute for Evolutionary Biology, Plön, Germany

2003-2009    • PhD in Developmental Biology, Stanford University, Stanford CA, USA

1999-2003    • BA (Honors) in Molecular Biology and Biochemistry

Wesleyan University, Middletown CT, USA

2001            • Research Intern, LION Bioscience AG, Heidelberg, Germany

2000            • Research Assistant, Mount Desert Island Biological Laboratory

Honours and Awards


2010-2012     • Postdoctoral Fellow, VolkswagenStiftung – Evolutionary Biology

2011             • Young Researcher at the Lindau Nobel Meeting (supported by the Max Planck Society and the Böhringer Ingelheim Stiftung)

2010             • Walter M. Fitch Prize Finalist (PhD Dissertation Award Symposium)

2010             • EMBO Longterm Fellowship (gratefully declined)

2010             • Alexander von Humboldt Research Fellowship (gratefully declined)

2008             • AAAS/Science Program for Excellence in Science

2003-2006     • Affymetrix Bio-X Fellow, Stanford Graduate Fellowship (pre-doctoral fellowship)

2003             • Phi Beta Kappa Honour Society (Gamma Chapter)

2003             • Scott Biomedical Prize for Excellence in Biology (undergraduate subject award)

1999-2003     • Freeman Asian Scholar (undergraduate fellowship)

2000, 2002     • Howard Hughes Summer Research Fellowship

2001             • CDS International Summer Internship Program (biotech intern in Heidelberg, Germany)

1999             • Hong Kong SCMP Student Linguist of the Year

1999             • Dr. Li Fook Sin Scholarship

  • Genetic dissection of gigantism in laboratory and wild mice
  • Developmental and chromosome dynamics of long-range enhancers

The Molecular Basis of Parallel Evolution

2010 – Chan YF, Marks ME, Jones FC, Villarreal G Jr., Shapiro MD, Brady SD, Southwick AM, Absher DM, Grimwood J, Schmutz J, Myers RM, Petrov DA, Jónsson B, Schluter D, Bell MA, Kingsley DM. Adaptive evolution of pelvic reduction in sticklebacks by recurrent deletion of a Pitx1 enhancer. Science (Article) 327 (5963): 302-305.

  • Featured in Science, Nature
  • Section highlight in Developmental Biology, 9th Ed (p. 686) by S. Gilbert
  • Featured in NPR Science Friday & New York Times Science
  • Selected by Faculty of 1000 (FFa – 10; Must Read), Nature Journal Club

The Genetic Architecture of Parallel Evolution and Complex Trait Evolution

2012 – Jones FC*, Grabherr MG*, Chan YF*, Russell P*, Mauceli E., Johnson J, Pirun M, Zody MC, White S, Birney E, Searle S, Schmutz J, Grimwood J, Dickson MC, Myers RM, Miller CT, Summers BR, Knecht AK, Brady SD, Zhang H, Pollen AA, Howes T, Amemiya C, Broad Institute Genome Sequencing Platform and Whole Genome Assembly Team, Lander ES, Di Palma F, Lindblad-Toh K, Kingsley DM. The genomic basis of adaptive evolution in threespine sticklebacks. Nature (Article). 484 (7392): 55-61. (* co-first authorship)

  • Featured in Nature

2012 – Chan YF, Jones FC, McConnell E, Bryk J, Bünger L, Tautz D. Parallel selection mapping using artificially selected mice reveals bodyweight control genes. Current Biology. 22 (9): 794-800.

  • Featured in Nature Review Genetics, Current Biology

2009 – Kitano J, Ross JA, Mori S, Kume M, Jones FC, Chan YF, Absher DM, Grimwood J, Schmutz J, Myers RM, Kingsley DM, Peichel CL. A role for neo-sex chromosomes in stickleback speciation. Nature (Article) 461 (7267): 1079-1083.

2011 – Jones FC, Chan YF, Schmutz J, Grimwood J, Brady SD, Southwick AM, Absher DM, Myers RM, Reimchen TE, Deagle BE, Schluter D, Kingsley DM. A genome-wide genotyping array reveals patterns of global and repeated species pair divergence in sticklebacks. Current Biology. 22 (1): 83-90.

2011 – Greenwood AK, Jones FC, Chan YF, Brady SD, Absher DM, Grimwood J, Schmutz J, Myers RM, Kingsley DM, Peichel CL. The genetic basis of cryptic pigment patterns in juvenile threespine sticklebacks. Heredity. 107: 155-166.

2012 – Wark AR, Mills MG, Dang L-H, Chan YF, Jones FC, Brady SD, Absher DM, Grimwood J, Schmutz J, Myers RM, Kingsley DM, Peichel CL. Genetic architecture of variation in the lateral line sensory system of threespine sticklebacks. G3: Genes, Genomes, Genetics. 2 (9): 1047-1056.

2011 – Deagle, BE, Jones FC, Chan YF, Absher DM, Kingsley DM, Reimchen TE. Population genomics of parallel phenotypic evolution in stream–lake stickleback. Proceedings of the Royal Society B. 279 (1732): 1277-1286.

Evolutionary Genetics/Genomics and Parallel Evolution

2012 – Chan YF. Parallel evolution: hearing echoes. Heredity 108: 471-472. (News & Commentary)

2012 – Chan YF. A personal primer for modern biology. Trends in Ecology and Evolution. DOI: 10.1016/j.tree.2012.07.012. (Book review)