Postdoctoral Fellow in complex trait genetics and tissue engineering



Postdoctoral position in complex trait genetics and tissue engineering



A postdoctoral position in complex trait genetics and tissue engineering is available in the Chan Lab at the Max Planck Institute in Tübingen, Germany as part of a Max Planck and ERC-funded research team investigating gene network evolution in mouse tissue culture models.


Your role:  You will be the main driver in our exciting new project in studying gene network evolution using in vitro crosses of tissues from interspecific mouse hybrids. You will be responsible for the derivation of specialized embryonic stem cell and iPSC lines and the generation of recombinant inbred mapping panels from these lines. You will adopt tissue engineering techniques to assay expression and tissue phenotypes. You will analyze DNA and RNAseq data to dissect the genetic architecture of gene expression evolution in mouse tissue and organoid models. You will have the opportunity to develop independent research ideas within our mouse in vitro cross framework.

Requirements: You will have a PhD or equivalent degree in the areas of genetics, molecular biology or regenerative medicine. You should demonstrate expertise and experience in tissue engineering techniques. We are looking for a strong track-record and demonstrated excellence in creative and interdisciplinary thinking. A strong bioinformatics or statistical background will be advantageous. A background in evolutionary biology will be helpful, but not a requirement. We are interested in candidates who are keen to apply and develop new genetic tools and technologies. Passion for research, team spirit and enthusiasm are essential.

Our Team: We are a multidisciplinary team that focuses on the systems biology of development and evolution in mice, combining population and functional genomics with molecular biology and tissue engineering techniques to study the evolution of gene regulatory network in mouse and its close relatives. Our research group is funded by the European Research Council (ERC) and the Max Planck Society and is located on the Max Planck campus in Tübingen, Germany. Our campus hosts world-class research groups and operates state-of-the-art sequencing and other core facilities. English is the working language. All seminars and communications are in English.

Our Offer: The position is available for an initial 2 years with the possibility of extension based on performance. Salary and benefits are according to the German public service pay scale (TVöD Bund up to and including E13) and are commensurate with training and experience.

The Max Planck Society seeks to increase the number of women in areas where they are underrepresented, and therefore explicitly encourages women to apply. The Max Planck Society is committed to employing more handicapped individuals and especially encourages them to apply.

See Lazzarano et al., Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells. Proc Nat Acad Sci, 2018. doi: 10.1073/pnas.1717474115

To Apply: Consideration of applications will begin on 15th April 2018, and will remain open until filled. Please send your application with 1. a statement of research interests and why you have applied for this position, 2. your CV, and 3. three reference letters to Dr Frank Chan at or the postal address below. Incomplete applications will not be considered.   


Dr Frank Chan, Friedrich Miescher Laboratory of the Max Planck Society, Spemannstrasse 39, 72076 Tübingen, Germany.