Wolfram Antonin and Iain W Mattaj (2005)

Nuclear pore complexes: round the bend?

Nature Cell Biology, 7(1):10-2.
Nuclear pore complexes intuitively seem functionally analogous to transmembrane channels. Recent bioinformatic analysis, however, suggests a quite different evolutionary relationship: one between nuclear pore complexes and vesicle coat components. This has led to the provocative hypothesis that these distinct structures share a common role in bending membranes.